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MRP3 has also been reported to transport glutathione S-conjugates 60

This group includes liberated Hb and an enzyme called arginase 1 8

[35] In rodent pre-clinical studies, urinary and serum alpha GST have been shown to be sensitive and specific indicators of renal proximal tubular and hepatocyte necrosis respectively

Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, et al

Dieterle, M

If taking NAC on an empty stomach causes stomach pain or mild nausea, it is perfectly acceptable to take it with a small amount of food to improve tolerability